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Text File  |  1987-10-07  |  592b  |  16 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, TRIMETHOPRIM/SULFA DOSAGE
  3.          SHOULD BE CAREFULLY ADJUSTED TO AVOID TOXICITY (NEPHRO-
  4.          TOXICITY, ANTIFOLATE ACTION).
  5.           
  6.          SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE
  7.          ADJUSTED BASED ON THE PATIENT'S CREATININE CLEARANCE:
  8.           
  9.                       CREATININE     DOSAGE INTERVAL
  10.                        CLEARANCE         METHOD
  11.                       (ML/MINUTE)
  12.           
  13.                         10-50           18 hours
  14.                          <10            24 hours
  15.           
  16.